HPLC Columns and Cartridges

Achieve exceptional peak shape and resolution for your HPLC and LC/MS applications with Thermo Scientific™ Hypersil GOLD™ HPLC columns. These endcapped, ultrapure, silica-based columns deliver significant reduction in peak tailing using generic gradients with C18 selectivity.

Retain and resolve polar analytes using Thermo Scientific™ Hypersil GOLD™ aQ Polar Endcapped C18 columns. These columns provide excellent peak shape, even with challenging reversed phase separations using highly aqueous mobile phases.

Choose Thermo Scientific™ Accucore™ Biphenyl LC Columns for fast and reliable separation of critical pairs and isomers. These columns provide unique selectivity for aromatic and moderately polar analytes. Their optimized packing offers a rugged platform for a variety of matrices.

Achieve repeatable and consistent liquid chromatography (LC) separations using Thermo Scientific™ Syncronis™ C18 columns. Highly pure, high surface area silica and dense stationary phase coverage minimize secondary interactions and ensure robust, high-resolution separations.

BetaBasic columns are highly efficient and reproducible for small molecules, peptides and protein digests

For a robust, general-purpose column to use in a wide range of applications, choose Thermo Scientific™ Hypersil™ BDS C18 HPLC Columns. These economical columns feature reduced silanol activity and provide exceptional reliability for QA/QC labs.

Use Thermo Scientific™ ProPac™ WCX-10 LC Columns to provide exceptionally high resolution for separations of proteins and their variants. Based on stationary phases composed of 10μm nonporous polymeric beads, ProPac columns resolve isoforms that differ by a single charged residue.

Thermo Scientific™ HyPURITY™ Cyano HPLC Columns are based on the HyPURITY 190Å silica—the highest quality silica available and essentially metal-free with exceptionally stablity at high and low pH. The rugged and robust manufacturing process ensures reproducibility and optimum quality, batch after...

Drop-in guard cartridges offer convenience, economy and effective protection for extending column lifetime.

Optimized for MS detection, Thermo Scientific™ Accucore™ RP-MS LC Columns are an excellent combination of speed and quality of separation. Based on Core Enhanced Technology, Accucore columns provide fast, high-resolution separations—without the elevated backpressures required by sub-2μm particles.

Use the new Thermo Scientific™ MAbPac™ Reversed Phase columns for high-performance reversed-phase (RP) HPLC and LC/MS characterization of monoclonal antibodies (mAbs), fragments, variants, antibody drug conjugates (ADCs), PEGylated proteins, and bispecific proteins.

For surfactant analysis using high-sensitivity detection, the column of choice is the Thermo Scientific™ Acclaim™ Surfactant Plus LC Columns. This new generation of high-efficiency silica-based columns features exceptionally low bleed for use with charged aerosol detectors (CAD) and mass...

Improve the separation efficiency in your reversed-phase applications with Thermo Scientific™ Acclaim™ 120 C18 columns. These columns feature an ultrapure silica substrate with extremely low metal content to minimize tailing effects and deliver symmetrical peak shapes.

For reversed-phase separation of analytes with moderate hydrophobicity, use Thermo Scientific™ Acclaim™ 120 C8 LC columns. These high-performance columns provide selectivity that is similar to Acclaim 120 C18 columns with a predictable elution order but less retention.

Separate a wide range of enantiomers with Thermo Scientific™ Hypersil™ Chiral HPLC columns, designed for separations of neutral, acidic and basic racemates in normal phase. These chiral columns can help ensure your purification needs are met by resolving racemic mixtures and potential contaminants...