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Prednisolone, 99%, Thermo Scientific Chemicals
Prednisolone, or metacortandralone, CAS # 50-24-8, is a synthetic glucocorticoid.
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Catalog number FSA449470250
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Quantity:
25 g
Packaging:
Glass Bottle
Specifications
Chemical Name or MaterialPrednisolone
CAS50-24-8
Health Hazard 1GHS Signal Word: Danger
Health Hazard 2GHS H Statement
May damage the unborn child.
May damage the unborn child.
Health Hazard 3GHS P Statement
Use personal protective equipment as required.
Do not handle until all safety precautions have been read and understood.
Use personal protective equipment as required.
Do not handle until all safety precautions have been read and understood.
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This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
• Prednisolone is a derivative of prednisone with an oxo to beta-hydroxy reduction at position 11
• Prednisolone binds cell surface receptors and is transported to the nucleus, where it binds certain nuclear receptors responsible for transcription of proinflammatory cytokines
Applications
• Prednisolone can be used for laboratory research on tumor growth and prevention
• Prednisolone may also be used for developmental and endocrine research, in vivo or in vitro
RUO – Research Use Only
General References:
- Waldrop, M.A.; Karingada, C.; Storey, M.A.; Powers, B.; Lammarino, M.A.; Miller, N.F.; Alfano, L.N.; Noritz, G.; Rossman, I.; Ginsberg, M.; Mosher, K.A., Broomall, E.; Goldstein, J.; Bass, N.; Lowes, L.P.; Tsao, C.Y.; Mendell, J.R.; Connolly, A.M. Gene Therapy for Spinal Muscular Atrophy: Safety and Early Outcomes. Pediatrics. 2020, 146(3), e20200729.
- Koumpa, F.S.; Forde, C.T.; Manjaly, J.G. Sudden irreversible hearing loss post COVID-19. BMJ Case Rep. 2020, 13(11), e238419.