Bacitracin, potency min. 60 Units/mg

Name: Bacitracin, potency min. 60 Units/mg
SKU: FSA226100050

Bacitracin, CAS # 1405-87-4, is cyclic polypeptide-based antibiotic which exhibits activity against microbes causing pneumonia, skin, and eye infections.

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Quantity:

5 g

25 g

Packaging:

Glass Bottle

Catalog number FSA226100050

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Quantity:

5 g

Packaging:

Glass Bottle

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Specifications

Chemical Name or MaterialBacitracin

TypeBacitracin

Physical FormPowder

CAS1405-87-4

Health Hazard 1Warning

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• Bacitracin is a mixture of at least nine different cyclic polypeptides, originally isolated from Bacillus bacteria in 1945

• Bacitracins work by binding divalent metal cations and preventing the hydrolysis of lipids into usable cell wall components

Applications

• Bacitracin has been paired with nanoparticles in some laboratory studies to increase its effectivity

• It is suitable for the laboratory study of bacterial resistance, infection, and cross-reactivity

RUO – Research Use Only

General References:

Tay, W.M.; Epperson, J.D.; da Silva, G.F.; Ming, L.J. 1H NMR, mechanism, and mononuclear oxidative activity of the antibiotic metallopeptide bacitracin: the role of D-Glu-4, interaction with pyrophosphate moiety, DNA binding and cleavage, and bioactivity. J Am Chem Soc. 2010, 28, 132(16), 5652-61.
Karala, A.R.; Ruddock, L.W. Bacitracin is not a specific inhibitor of protein disulfide isomerase. FEBS J. 2010, 277(11), 2454-62.