JP 1302 dihydrochloride, Tocris Bioscience™
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JP 1302 dihydrochloride, Tocris Bioscience™
JP 1302 dihydrochloride, Tocris Bioscience™
JP 1302 dihydrochloride, Tocris Bioscience™

JP 1302 dihydrochloride, Tocris Bioscience™

Potent and selective α2C antagonist
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Catalog NumberQuantity
EYE26665050 mg
Catalog number EYE266650
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50 mg
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Specifications
Chemical Name or MaterialJP 1302 dihydrochloride
CAS1259314-65-2
Recommended StorageStore at -20°C
Molecular FormulaC24H26Cl2N4
Quantity50 mg
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α2C-adrenoceptor antagonist that displays ∽ 50-fold selectivity over other α2-adrenoceptor subtypes (Ki values are 28, 1470, 1700 and 3150 nM for human α2C, α2B, α2D and α2A subtypes respectively). Potently antagonizes adrenalin-stimulated 35GTPγS binding in vitro (KB = 16 nM) and produces antidepressant and antipsychotic-like effects in vivo.