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5-Fluoro-2'-deoxyuridine, 98+%
CAS: 50-91-9 | C9H11FN2O5 | 246.19 g/mol
| Catalog Number | Quantity |
|---|---|
| ALFL16497.MC | 100 mg |
Catalog number ALFL16497.MC
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Quantity:
100 mg
Specifications
Chemical Name or Material5-Fluoro-2'-deoxyuridine
CAS50-91-9
Health Hazard 1H301-H315-H319-H341
Health Hazard 2GHS H Statement
H360-H341-H302
May damage fertility or the unborn child.
Suspected of causing genetic defects.
Harmful if swallowed.
H360-H341-H302
May damage fertility or the unborn child.
Suspected of causing genetic defects.
Harmful if swallowed.
Health Hazard 3P201-P202-P264b-P270-P280i-P281-P301+P310-P302+P352-P305+P351+P338-P308+P313-P330-P332+P313-P362-P501c
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5-Fluoro-2'-deoxyuridine acts as an antiviral and antineoplastic agent. It is also employed for renal function diagnosis. Further, it is used as an experimental anticancer agent, which shows activity against a variety of malignant neoplasms. It is also used as an inhibitor of thymidylate synthetase and DNA synthesis. In addition to this, it plays an important role in the treatment of colorectal cancer.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Solubility
Soluble in water, alcohol, isopropyl alcohol, methanol, aqueous buffers, acetone, dimethyl sulfoxide, and ethanol. Insoluble in ether, benzene and chloroform.
Notes
Store in a cool place.Incompatible with strong oxidizing agents and strong bases.
Soluble in water, alcohol, isopropyl alcohol, methanol, aqueous buffers, acetone, dimethyl sulfoxide, and ethanol. Insoluble in ether, benzene and chloroform.
Notes
Store in a cool place.Incompatible with strong oxidizing agents and strong bases.
RUO – Research Use Only
General References:
- Rooney, J. P.; Luz, A. L.; Gonzalez-Hunt, C. P.; Bodhicharla, R.; Ryde, I. T.; Anbalagan, C.; Meyer, J. N. Effects of 5'-fluoro-2-deoxyuridine on mitochondrial biology in Caenorhabditis elegans. Exp. Gerontol. 2014, 56, 69-76.
- Kruspe, S.; Hahn, U. An Aptamer Intrinsically Comprising 5-Fluoro-2'-deoxyuridine for Targeted Chemotherapy. Mol. BioSyst. 2014, 53 (39), 10541-10544.