Search Thermo Fisher Scientific
Element Search
Structure Search
Thermo Scientific Chemicals
N,N-Dimethylformamide dimethyl acetal, 94%
CAS: 4637-24-5 | C5H13NO2 | 119.16 g/mol
| Catalog Number | Quantity |
|---|---|
| ALFA15350.14 | 25 g |
Catalog number ALFA15350.14
View Price:Sign InSign in to see your account pricing. Need an account? Register with us today.
Quantity:
25 g
Specifications
Chemical Name or MaterialN,N-Dimethylformamide dimethyl acetal
CAS4637-24-5
Health Hazard 1H225-H317-H318-H332-H361
Health Hazard 2GHS H Statement
H225-H302-H332-H315-H319-H335
Highly flammable liquid and vapour.
Harmful if swallowed.
Harmful if inhaled.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
H225-H302-H332-H315-H319-H335
Highly flammable liquid and vapour.
Harmful if swallowed.
Harmful if inhaled.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Health Hazard 3P201-P202-P210-P233-P240-P241-P242-P243-P261-P271-P272-P280g-P281-P303+P361+P353-P304+P340-P305+P351+P338-P308+P313-P310-P312-P333+P313-P363-P370+P378q-P372-P374-P380-P501c
View more
N,N-Dimethylformamide dimethyl acetal is used as an intermediate in the formation of pyridine derivatives, which exhibits inhibition against PI3 kinase p110alfa enzymes. It is utilized for the derivatization of primary sulfonamides and trifluoroacetic acid. It is also used in the preparation of formamidine derivatives. It is used as a reagent for n-dimethylaminomethylene and methyl esters. Further, it is used to catalyze the coupling of epoxides with carbon dioxide to prepare cyclic carbonates.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
N,N-Dimethylformamide dimethyl acetal is used as an intermediate in the formation of pyridine derivatives, which exhibits inhibition against PI3 kinase p110alfa enzymes. It is utilized for the derivatization of primary sulfonamides and trifluoroacetic acid. It is also used in the preparation of formamidine derivatives. It is used as a reagent for n-dimethylaminomethylene and methyl esters. Further, it is used to catalyze the coupling of epoxides with carbon dioxide to prepare cyclic carbonates.
Solubility
Miscible with most organic solvents.
Notes
Moisture sensitive. Incompatible with strong oxidizing agents and acids.
N,N-Dimethylformamide dimethyl acetal is used as an intermediate in the formation of pyridine derivatives, which exhibits inhibition against PI3 kinase p110alfa enzymes. It is utilized for the derivatization of primary sulfonamides and trifluoroacetic acid. It is also used in the preparation of formamidine derivatives. It is used as a reagent for n-dimethylaminomethylene and methyl esters. Further, it is used to catalyze the coupling of epoxides with carbon dioxide to prepare cyclic carbonates.
Solubility
Miscible with most organic solvents.
Notes
Moisture sensitive. Incompatible with strong oxidizing agents and acids.
RUO – Research Use Only
General References:
- Lee, H. J.; Lee, S.; Yu, J.; Kim, J. N. Vinylogous N,N-dimethylaminomethylenation of 3-[(1-substituted) ethylidene]-oxindoles with N,N-dimethylformamide dimethylacetal. Tetrahedron Lett. 2014, 55 (15), 2450-2454.
- Prek, B.; Grošelj, U.; Kasunič, M.; Zupančič, S.; Svete, J.; Stanovnik, B. Reactions of Methyl Ketones and (Hetero)arylcarboxamides with N, N-Dimethylacetamide Dimethyl Acetal. A Simple Metal-Free Synthesis of 2, 4, 6-Trisubstituted Pyridines. Aust. J. Chem. 2015, 68 (2), 184-195.