Diethylamine hydrochloride, 99%, Thermo Scientific Chemicals

Name: Diethylamine hydrochloride, 99%, Thermo Scientific Chemicals
SKU: ALFA13637.30

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1000 g

Catalog number ALFA13637.30

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Specifications

Chemical Name or MaterialDiethylamine hydrochloride

CAS660-68-4

Health Hazard 1H315-H319-H335

Health Hazard 2GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.

Health Hazard 3P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c

Diethylamine hydrochloride acts as a precursor of atrazine and lysergic acid diethylamide. It is also used as a reactant in the production of dyes and pharmaceutical compounds such as ranitidine. Further, it is used in Mannich reaction with paraformaldehyde. In addition to this, it is employed in the synthesis of diethylaminoethyl (DEAE) cottons by reacting with cotton cellulose in the presence of sodium hydroxide.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Diethylamine hydrochloride acts as a precursor of atrazine and lysergic acid diethylamide. It is also used as a reactant in the production of dyes and pharmaceutical compounds such as ranitidine. Further, it is used in Mannich reaction with paraformaldehyde. In addition to this, it is employed in the synthesis of diethylaminoethyl (DEAE) cottons by reacting with cotton cellulose in the presence of sodium hydroxide.

Solubility
Soluble in water.

Notes
Hygroscopic. Incompatible with oxidizing agents.

RUO – Research Use Only

General References:

For Mannich reaction with paraformaldehyde and acetone, see: Org. Synth. Coll., 4, 281 (1963).
Xiao, J.; Huang, Y.; Song, Z.; Feng, W. Facile catalyst-free synthesis of 2-vinylquinolines via a direct deamination reaction occurring during Mannich synthesis. RSC Adv. 2015, 5 (120), 99095-99098.
Zavozin, A. G.; Ignat'ev, N. V.; Schulte, M.; Zlotin, S. G. Synthesis of novel tridentate pyrazole-bipyridine ligands for Co-complexes as redox-couples in dye-sensitized solar cells. Tetrahedron 2015, 71 (45), 8551-8556.