2-Nitrobenzaldehyde, 98+%
2-Nitrobenzaldehyde, 98+%
2-Nitrobenzaldehyde, 98+%
2-Nitrobenzaldehyde, 98+%
Thermo Scientific Chemicals

2-Nitrobenzaldehyde, 98+%

CAS: 552-89-6 | C7H5NO3 | 151.121 g/mol
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Catalog NumberQuantity
ALFA11501.1425 g
Catalog number ALFA11501.14
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25 g
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Specifications
Chemical Name or Material2-Nitrobenzaldehyde
CAS552-89-6
Health Hazard 1H302-H315-H319-H335
Health Hazard 2GHS H Statement
H302-H315-H319-H335
Harmful if swallowed.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Health Hazard 3P261-P264b-P270-P271-P280-P301+P312-P302+P352-P304+P340-P305+P351+P338-P312-P330-P332+P313-P362-P501c
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2-Nitrobenzaldehyde is used as a starting material in synthetic chemistry. It is used as an intermediate during the synthesis of Indigo dye. It is involved in the preparation of colorants such as Indigo carmine. Further, it serves as a useful photoremovable protecting group as well as utilized in the preparation of o-nitrophenylethylene glycol.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
2-Nitrobenzaldehyde is used as a starting material in synthetic chemistry. It is used as an intermediate during the synthesis of Indigo dye. It is involved in the preparation of colorants such as Indigo carmine. Further, it serves as a useful photoremovable protecting group as well as utilized in the preparation of o-nitrophenylethylene glycol.

Solubility
Insoluble in water.

Notes
Incompatible with strong oxidizing agents and strong bases.
RUO – Research Use Only

General References:

  1. The nitro group can be displaced by nucleophiles. Thus, tert-butanethiol gives 2-tert-butylthiobenzaldehyde, a useful intermediate for thiocoumarins and other sulfur-containing heterocycles: Synthesis, 56 (1978).
  2. For reduction with FeSO4 to the unstable 2-aminobenzaldehyde, see: Org. Synth. Coll., 3, 56 (1955).
  3. Cummings, M. M.; Söderberg, B. C. G. Reexamination of the Bromination of 2-Nitrobenzaldehyde with NBS or NaBr-NaIO4 in Sulfuric Acid. Synth. Commun. 2014, 44 (7), 954-958.
  4. Bouya, H.; Errami, M.; Salghi, R.; Ebenso, E. E.; Zarrouk, A.; Chakir, A.; Hammouti, B. Electrochemical Oxidation of 2-Nitrobenzaldehyde on Boron-Doped Diamond Anodes. Int. J. Electrochem. Sci. 2013, 8, 7468-7478.