Cefoxitin sodium salt, 94%

Name: Cefoxitin sodium salt, 94%
SKU: FSA455280050

Cefoxitin sodium salt, CAS # 33564-30-6, is a β-lactam, second-generation cephalosporin compound showing bactericidal activity against Bacteroides, gram-negative bacteria, including strains of P. mirabilis, P. vulgaris, E. coli, S. typhimurium, and S. enteritidis. | CAS: 33564-30-6 | C16H16N3NaO7S2 | 449.428 g/mol

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Catalog number FSA455280050

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Specifications

Chemical Name or MaterialCefoxitin sodium salt

TypeCefoxitin Sodium Salt

CAS33564-30-6

Health Hazard 1Warning

Health Hazard 2GHS H Statement May cause an allergic skin reaction.

This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

Cefoxitin sodium salt is resistant to β-lactamase
It binds and inactivates penicillin-binding proteins (PBP) located on the inner membrane of the bacterial cell wall thus interfering with the cross-linkage of peptidoglycan chains necessary for bacterial cell wall strength and rigidity

Applications

Cefoxitin sodium salt is the sodium salt form of cefoxitin derived from cephamycin C
It is a β-lactam, second-generation cephalosporin compound with bactericidal activity against numerous species such as Bacteroides, gram-negative bacteria, including strains of P. mirabilis, P. vulgaris, E. coli, S. typhimurium, and S. enteritidis
Cefoxitin increases survival in mice infected with S. aureus, S. pyogenes, and K. pneumoniae

RUO – Research Use Only

General References:

Brogden, R.; Heel, R.; Speight, T.; Avery, G. Cefoxitin: a review of its antibacterial activity, pharmacological properties and therapeutic use. Drugs. 1979, 17 (1), 1-37.
Miller, A.K., Celozzi, E., Kong, Y., et al. Cefoxitin, a semisynthetic cephamycin antibiotic: In vivo evaluation. Antimicrob. Agents Chemother. 1974, 5, (1), 33-37.