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Deoxycholic acid, sodium salt, 99%, extra pure
Deoxycholic acid, sodium salt, CAS # 302-95-4, also designed as sodium deoxycholate, is a biological anionic bile acid detergent that is especially useful for disrupting and dissociating protein interactions. | CAS: 302-95-4 | C24H39NaO4 | 414.56 g/mol
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Catalog number FSA218591000
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Quantity:
100 g
Packaging:
Glass bottle
Specifications
Chemical Name or MaterialDeoxycholic acid, sodium salt
CAS302-95-4
Health Hazard 2GHS H Statement:
Harmful if swallowed.
May cause respiratory irritation.
Harmful if swallowed.
May cause respiratory irritation.
Health Hazard 3GHS P Statement:
Avoid breathing dust/fume/gas/mist/vapors/spray.
IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
WARNING: The information provided on this web site was developed in compliance with European Union (EU) regulations and is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling and use. It is not to be considered as either a warranty or quality specification.
Avoid breathing dust/fume/gas/mist/vapors/spray.
IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell.
WARNING: The information provided on this web site was developed in compliance with European Union (EU) regulations and is correct to the best of our knowledge, information and belief at the date of its publication. The information given is designed only as a guide for safe handling and use. It is not to be considered as either a warranty or quality specification.
ColorWhite to Cream
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This Thermo Scientific Chemicals brand product was originally part of the Acros Organics product portfolio. Some documentation and label information may refer to the legacy brand. The original Acros Organics product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
General Description
- The deoxycholic acid sodium salt is a bile acid choleretic and anionic detergent that allows the solubilization of fats for intestinal absorption
- The compound is an intermediate in the production of corticosteroids
- In animal models it has been shown that this compound can promote tyrosine phosphorylation of β-catenin and its translocation to the nucleus, promoting the activation of β-catenin signaling
Applications
- Deoxycholic acid is mainly useful for the extraction of membrane receptors, other plasma membrane proteins, nuclei isolation, solubilization and isolation of fats, and some components of biological membranes (in an active state)
- It has been used for chemical applications, mainly for the elution or regeneration of specific types of affinity columns. Furthermore, this compound can be used to prevent non-specific binding in affinity chromatography.
- It has been applied in the preparation of protein extracts for immunoblotting and immunoprecipitation of radiolabeled proteins
- Deoxycholic acid, sodium salt is also recommended for stripping endotoxins
RUO – Research Use Only