Methyl indole-3-carboxylate, 99%
Methyl indole-3-carboxylate, 99%
Methyl indole-3-carboxylate, 99%
Methyl indole-3-carboxylate, 99%
Thermo Scientific Chemicals

Methyl indole-3-carboxylate, 99%

CAS: 942-24-5 | C10H9NO2 | 175.187 g/mol
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Catalog NumberQuantity
ALFL14516.1425 g
Catalog number ALFL14516.14
Price (MYR)
492.00
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Quantity:
25 g
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Price (MYR)
492.00
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Specifications
Chemical Name or MaterialMethyl indole-3-carboxylate
CAS942-24-5
Health Hazard 1H315-H319-H335
Health Hazard 3P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
Melting Point149°C to 152°C
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Reactant used for preparation of nitric oxide synthesis (nNOS) inhibitors, protein kinase c alpha (PKCα) inhibitors, inhibitors of the C-terminal domain of RNA polymerase II as antitumor agents, kinase insert domain receptor (KDR) inhibitors, organocatalysts for the anti-Mannich reaction, very late antigen-4 (VLA-4) antagonists, inhibitors of Human 5-Lipoxygenase, serotonin 5-HT4 receptor antagonists and hyaluronidase inhibitors.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Reactant used for preparation of nitric oxide synthesis (nNOS) inhibitors, protein kinase c alpha (PKCα) inhibitors, inhibitors of the C-terminal domain of RNA polymerase II as antitumor agents, kinase insert domain receptor (KDR) inhibitors, organocatalysts for the anti-Mannich reaction, very late antigen-4 (VLA-4) antagonists, inhibitors of Human 5-Lipoxygenase, serotonin 5-HT4 receptor antagonists and hyaluronidase inhibitors.

Solubility
Slightly soluble methanol and dimethyl sulfoxide. Insoluble in water.

Notes
Store in cool. Keep container tightly closed in a dry and well-ventilated place. Store away from oxidizing agent.
RUO – Research Use Only

General References:

  1. Jane F. Djung et. al. The synthesis and evaluation of indolylureas as PKCα inhibitors. Bioorganic & Medicinal Chemistry2011, 19(8), 2742-2750.
  2. Takahiro Honda et. al. KDR inhibitor with the intramolecular non-bonded interaction: Conformation-activity relationships of novel indole-3-carboxamide derivatives. Bioorganic & Medicinal Chemistry Letters,. 2011, 21 (6), 1782-1785.