DL-Tryptophan, 99%

DL-Tryptophan, CAS # 54-12-6, is an α-amino acid that is commonly used in the synthesis of proteins. It is an essential amino acid precursor for the formation of serotonin, melatonin, and vitamin B3. | CAS: 54-12-6 | C11H12N2O2 | 204.23 g/mol

Catalog Number	Quantity
ALFL05936.14	25 g

Catalog number ALFL05936.14

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Specifications

Chemical Name or MaterialDL-Tryptophan

Melting Point∽280°C (decomposition)

CAS54-12-6

Recommended StorageAmbient temperatures

RTECS NumberYN6129200

DL-Tryptophan is an amino acid precursor of serotonin and melatonin. It is a dietary supplement for use as an antidepressant, anxiolytic, and sleep aid. DL-tryptophan also can be used as feed nutrition enhancer, antioxidants.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description

• DL-Tryptophan is an α-amino acid, and an essential amino acid precursor of serotonin, melatonin, and vitamin B3

Application

• DL-Tryptophan shows antioxidant activity• It has a role as a Daphnia magna metabolite

• It has been explored in in vitro studies to evaluate the antimicrobial and immunoregulatory functions on indoleamine 2,3-dioxygenase

• It has been used as a medium supplement in Psilocybe atrobrunnea and Psilocybe serbica for the synthesis of compounds

• It can be used as a medium supplement for culturing yeast

RUO – Research Use Only

General References:

Nayak BN, Buttar HS. Evaluation of the antioxidant properties of tryptophan and its metabolites in in vitro assay. J Complement Integr Med. 2016, 13, (2), 129-36.
Kent K. Stewart and Robert F. Doherty. Resolution of DL-Tryptophan by Affinity Chromatography on Bovine-Serum Albumin-Agarose Columns. Current Issue.1973,70 (10), 2850-2852.
H. R. Snyder; Curtis W. Smith. A Convenient Synthesis of dl-Tryptophan. J. Am. Chem. Soc.1944,66 (3), 350-351.
Schmidt SK, Siepmann S, Kuhlmann K, Meyer HE, Metzger S, Pudelko S, Leineweber M, Däubener W. Influence of tryptophan contained in 1-Methyl-Tryptophan on antimicrobial and immunoregulatory functions of indoleamine 2,3-dioxygenase. PLoS One. 2012, 7, (9), e44797.
Lenz C, Sherwood A, Kargbo R, Hoffmeister D. Taking Different Roads: l-Tryptophan as the Origin of Psilocybe Natural Products. Chempluschem. 2021, 86, (1), 28-35.