Gentamicin sulfate, 600 I.U./mg
Gentamicin sulfate, 600 I.U./mg
Gentamicin sulfate, 600 I.U./mg
Gentamicin sulfate, 600 I.U./mg
Thermo Scientific Chemicals

Gentamicin sulfate, 600 I.U./mg

Gentamicin sulfate, CAS # 1405-41-0, is an aminoglycoside mainly used to inhibit the growth of Gram-negative bacteria. | CAS: 1405-41-0
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Catalog number ALFJ62834.09
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Specifications
Chemical Name or MaterialGentamicin sulfate
TypeGentamicin Sulfate
Physical FormPowder
CAS1405-41-0
Health Hazard 1H317-H334
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Gentamycin Sulfate is a broad-spectrum, aminoglycoside antibiotic used for cell culture which inhibits protein synthesis in sensitive organisms. Reported to have activity against gram-negative bacteria, Pseudomonas aeruginosa, gram-positive Staphylococcus aureus and some mycoplasmas. Reported to have low toxicity to mammalian cells and viruses at certain concentrations, useful for long-term tissue culture studies with viruses. This compound is a mixture of Gentamycin c1, c1a and c2.

Research Use only: Not intended for animal or human diagnostic or therapeutic use.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

General Description
• Gentamicin sulfate is a bactericidal aminoglycoside antibiotic which shows activity against Gram-negative bacteria
• It works by inhibiting protein biosynthesis through binding the bacterial ribosome 30S subunit
Applications
• Gentamicin sulfate has been used in studies to determine wound healing due to its antibiotic and antifungal properties
• It has laboratory research applications in the study of a number of clinical conditions, including actinomycotic infection, appendicitis, cystic fibrosis, osteomyelitis, pelvic inflammatory disease, plague, gonorrhea, and tularemia

RUO – Research Use Only

General References:

  1. Hahn, H.; Salt, A.N.; Schumacher, U.; Plontke, S.K. Gentamicin concentration gradients in scala tympani perilymph following systemic applications. Audiol Neurootol. 2013; 18(6): 383-391.
  2. Chen, C.; Chen, Y.; Pinpin Wu, P.; Chen, B. Update on new medicinal applications of gentamicin: evidence-based review. J Formos Med Assoc. 2014; 113(2): 72-82.
  3. Bajpai, S.K.; Shah, F.F.; Bajpai, M. Dynamic release of gentamicin sulfate (GS) from alginate dialdehyde (AD)-crosslinked casein (CAS) films for antimicrobial applications. Des Monomers Polym. 2017; 20(1): 18-32.