Potassium phosphate is typically used as a component in the preparation of phosphate based buffers. It is convenient stock solution for making phosphate buffers. The pKa of 6.82 (25 C) for phosphate buffers make them a universal buffer for biological applications such as cell culture media, column eluent solutions and reagents used in molecular biology. Specific applications include buffers for protein purification, bioprocessing and diagnostic reagent production. Potassium salts are used where sodium content needs to be minimized or controlled.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Potassium phosphate is typically used as a component in the preparation of phosphate based buffers. It is convenient stock solution for making phosphate buffers. The pKa of 6.82 (25 C) for phosphate buffers make them a universal buffer for biological applications such as cell culture media, column eluent solutions and reagents used in molecular biology. Specific applications include buffers for protein purification, bioprocessing and diagnostic reagent production. Potassium salts are used where sodium content needs to be minimized or controlled.
Solubility
Fully miscible in water. Insoluble in ethanol.
Notes
Stable under recommended storage conditions. Store in cool, dry conditions in well sealed containers.
RUO – Research Use Only
General References:
- M.Stashkevych; E.Khomutov; Y.Dumanskiy; A.Matviyenko; I.Zinkovych. The influence of 5-fluorouracil on activity of thymidine phosphorylase in gastric adenocarcinoma and normal adjacent tissue. Experimental oncology. 2014, 36,(4), 267-270.
- M.Scuotto; M.Persico; M.Bucci; V.Vellecco; N.Borbone; E.Morelli; G.Oliviero; E.Novellino; G.Piccialli; G.Cirino; M.Varra; C.Fattorusso; L.Mayol. Outstanding effects on antithrombin activity of modified TBA diastereomers containing an optically pure acyclic nucleotide analogue. Organic & Biomolecular Chemistry. 2014, 12,(28), 5235-5242.