1H-Tetrazole, 0.45M in acetonitrile

Coupling reagent for preparation of polynucleotides | CAS: 288-94-8 | CH2N4 | 70.055 g/mol

Catalog Number	Quantity
ALFJ61034.AH	200 mL

Catalog number ALFJ61034.AH

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Quantity:

200 mL

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Specifications

Chemical Name or Material1H-Tetrazole

CAS288-94-8

Health Hazard 1H225-H302+H312+H332-H319

Health Hazard 2GHS H Statement
H225-H312-H332-H319
Highly flammable liquid and vapor.
Harmful in contact with skin.
Harmful if inhaled.
Causes serious eye irritation.

Health Hazard 3P210-P233-P240-P241-P242-P243-P261-P264b-P270-P271-P280-P301+P312-P303+P361+P353-P304+P340-P305+P351+P338-P312-P330-P363-P370+P378q-P501c

1H-Tetrazole is used as a bioisostere for the carboxylate group. It is also used as coupling reagent for preparation of polynucleotides.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
1H-Tetrazole is used as a bioisostere for the carboxylate group. It is also used as coupling reagent for preparation of polynucleotides.

Solubility
Miscible with water.

Notes
Incompatible with reducing agents and alkali metals.

RUO – Research Use Only

General References:

Frija, L. M. T A.; Ismael, A.; Cristiano, M. L. S. Photochemical Transformations of Tetrazole Derivatives: Applications in Organic Synthesis. Molecules 2010, 15 (5), 3757-3774.
Dabbagh, A. H.; Mansoori, Y. New azoic dyes containing (1H)-tetrazole and azido group. Dyes Pigm. 2002, 54 (1), 37-46.