Carbadox, 98+%
Thermo Scientific Chemicals

Carbadox, 98+%

CAS: 6804-07-5 | C13H10BrNO | 276.13 g/mol
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Catalog NumberQuantity
ALFJ60284.1425 g
Catalog number ALFJ60284.14
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Quantity:
25 g
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Specifications
Chemical Name or MaterialCarbadox
CAS6804-07-5
Health Hazard 1H228-H302-H350
Health Hazard 2GHS H Statement
H228-H350-H302
Flammable solid.
May cause cancer.
Harmful if swallowed.
Health Hazard 3P201-P202-P210-P240-P241-P264b-P270-P281-P301+P312-P308+P313-P330-P370+P378q-P501c
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Carbadox has been used to suppress aldosterone production, to study the spread of shiga toxin-producing Escherichia coli (STEC) strains, and to compare different antimicrobial activities. Carbadox is a quinoxaline-di-N-oxide antibiotic that is generally used in feed to swine to prevent dysentery and improve feed efficiency. It inhibits bacteria by intercalation and induction of mutations in bacterial genome.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
Carbadox has been used to suppress aldosterone production, to study the spread of shiga toxin-producing Escherichia coli (STEC) strains, and to compare different antimicrobial activities. Carbadox is a quinoxaline-di-N-oxide antibiotic that is generally used in feed to swine to prevent dysentery and improve feed efficiency. It inhibits bacteria by intercalation and induction of mutations in bacterial genome.

Solubility
Soluble in 1N NaOH (50 mg/ml), and water (partly).

Notes
Store in cool, dry place in a tightly sealed container. Store away from oxidizing agents.
RUO – Research Use Only

General References:

  1. T Hayashi, I Suenaga; N Narukawa; T Yamazaki. In vitro and in vivo activities of sedecamycin against Treponema hyodysenteriae. Antimicrobial Agents and Chemotherapy. 1988, 32 (4), 458-461.
  2. Torey Looft; Heather K Allen; Thomas A Casey; David P Alt; Thaddeus B Stanton. Carbadox has both temporary and lasting effects on the swine gut microbiota. Dyes and Pigments. 2014, 5, 276.