o-Benzoic sulfimide is used as a pharmaceutic flavor aid. It is used in high performance liquid chromatographic method for the simultaneous separation and determination of acesulfame potassium, saccharine and aspartame.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
o-Benzoic sulfimide is used as a pharmaceutic flavor aid. It is used in high performance liquid chromatographic method for the simultaneous separation and determination of acesulfame potassium, saccharine and aspartame.
Solubility
Soluble in water (3.3 g/L at 20°C).
Notes
Keep container tightly sealed. Store in cool, dry conditions in well sealed containers. Incompatible with oxidizing agents.
RUO – Research Use Only
General References:
- A.D. Magri.; G. D'Ascenzo.; S.Nunziante Cesaro.; E. Chiacchierini. Coordination compounds of biological interest: thermal properties of some compounds of saccharin (o-benzoic sulfimide) with divalent metal ions. Thermochimica Acta. 1980, 36 (3), 279-286.
- Joseph G. Lombardino. Preparation of substituted 1,2-benzoisothiazolin-3-one 1,1-dioxides (o-benzoic sulfimides). J. Org. Chem. 1971, 36 (13), 1843-1845.