4-Fluorobenzaldehyde, 98%
4-Fluorobenzaldehyde, 98%
4-Fluorobenzaldehyde, 98%
4-Fluorobenzaldehyde, 98%
Thermo Scientific Chemicals

4-Fluorobenzaldehyde, 98%

CAS: 459-57-4 | C7H5FO | 124.114 g/mol
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Quantity:
100 g
25 g
Catalog number ALFA15383.22
Price (MYR)
684.00
EA
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Quantity:
100 g
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Price (MYR)
684.00
EA
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Specifications
Chemical Name or Material4-Fluorobenzaldehyde
CAS459-57-4
Health Hazard 1H226-H315-H319-H335
Health Hazard 2GHS H Statement
H226-H315-H319-H335
Flammable liquid and vapour.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Health Hazard 3P210-P233-P235-P240-P241-P242-P243-P261-P264b-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P332+P313-P363-P370+P378q-P501c
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4-Fluorobenzaldehyde is used in the preparation of pyrazolopyridine derivative, which finds application as mitogen-activated protein kinase (MAPK) inhibitor. It also serves as a synthetic intermediate in the preparation of pharmaceutical compounds.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
4-Fluorobenzaldehyde is used in the preparation of pyrazolopyridine derivative, which finds application as mitogen-activated protein kinase (MAPK) inhibitor. It also serves as a synthetic intermediate in the preparation of pharmaceutical compounds.

Solubility
Immiscible with water.

Notes
Air sensitive. Incompatible with strong bases, strong oxidizing agents and strong reducing agents.
RUO – Research Use Only

General References:

  1. For a facile route to 4-aryloxy phenols (Cu catalyzed substitution then Baeyer-Villiger reaction) see: Synthesis, 63 (1991). Ketones behave similarly.
  2. Dar, B. A.; Pandey, N.; Singh, S.; Bamezai, R. K.; Sharma, M.; Vishwakarma, R. A.; Singh, B. Heterogeneous reusable catalyst, ultrasound energy, and no solvent: a quick and green recipe for one-pot synthesis of beta-phosphonomalononitriles at room temperature. Tetrahedron Lett. 2014, 53 (3), 623-628.
  3. Barbuceanu, S. F.; Draghici, C.; Barbuceanu, F.; Bancescu, G.; Saramet, G. Design, Synthesis, Characterization and Antimicrobial Evaluation of Some Heterocyclic Condensed Systems with Bridgehead Nitrogen from Thiazolotriazole Class. Chem. Pharm. Bull. 2014, 63 (9), 694-700.