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N-Methyl-N-(trimethylsilyl)trifluoroacetamide, 97%
CAS: 24589-78-4 | C6H12F3NOSi | 199.25 g/mol
| Catalog Number | Quantity |
|---|---|
| ALFA13141.14 | 25 g |
Catalog number ALFA13141.14
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Quantity:
25 g
Specifications
Chemical Name or MaterialN-Methyl-N-(trimethylsilyl)trifluoroacetamide
CAS24589-78-4
Health Hazard 1H226-H315-H319-H335
Health Hazard 2GHS H Statement
H226-H315-H319-H335
Flammable liquid and vapour.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
H226-H315-H319-H335
Flammable liquid and vapour.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Health Hazard 3P210-P233-P235-P240-P241-P242-P243-P261-P264b-P271-P280-P303+P361+P353-P304+P340-P305+P351+P338-P312-P332+P313-P363-P370+P378q-P501c
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N-Methyl-N-(trimethylsilyl)trifluoroacetamide is used as a silylating reagent that forms volatile derivatives for GC-MS analysis. It acts as a pharmaceutical intermediate and metabolite of Famprofazone in humans. It is also used in the detection of steroid hormones 17-alfa-ethynylestradiol and estrone.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
N-Methyl-N-(trimethylsilyl)trifluoroacetamide is used as a silylating reagent that forms volatile derivatives for GC-MS analysis. It acts as a pharmaceutical intermediate and metabolite of Famprofazone in humans. It is also used in the detection of steroid hormones 17-alfa-ethynylestradiol and estrone.
Solubility
Immiscible with water.
Notes
Moisture sensitive. Store in a cool place. Incompatible with strong oxidizing agents and strong acids.
N-Methyl-N-(trimethylsilyl)trifluoroacetamide is used as a silylating reagent that forms volatile derivatives for GC-MS analysis. It acts as a pharmaceutical intermediate and metabolite of Famprofazone in humans. It is also used in the detection of steroid hormones 17-alfa-ethynylestradiol and estrone.
Solubility
Immiscible with water.
Notes
Moisture sensitive. Store in a cool place. Incompatible with strong oxidizing agents and strong acids.
RUO – Research Use Only
General References:
- Powerful silylating agent for a wide range of functional groups: J. Chromat., 115, 591 (1975); 134, 387 (1977); Chromatographia, 9, 440 (1976). See Appendix 4.
- Cabanelas, D. G.; Wright, L. P.; Paetz, C.; Onkokesung, N.; Gershenzon, J.; Concepción, M. R.; Phillips, M. A. The diversion of 2-C-methyl-d-erythritol-2, 4-cyclodiphosphate from the 2-C-methyl-d-erythritol 4-phosphate pathway to hemiterpene glycosides mediates stress responses in Arabidopsis thaliana. Plant J. 2015, 82 (1), 122-137.
- Wong, A. S. Y.; Ho, E. N. M.; Wan, T. S. M.; Lam, K. K. H.; Stewart, B. D. Metabolic studies of oxyguno in horses. Anal. Chim. Acta 2015, 891, 190-202.