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Pyrrole-2-carboxaldehyde, 99%
Pyrrole-2-carboxaldehyde, 99%, C5H5NO, CAS Number-1003-29-8, 2-pyrrolecarboxaldehyde, 2-pyrrolecarbaldehyde, 2-pyrrolaldehyde, 1h-pyrrole-2-carboxaldehyde, alpha-pyrrolaldehyde, 2-formylpyrrole, 2-pyrrolylcarboxaldehyde, pyrrole-2-aldehyde, pyrrole-2-carboxaldehyde, pyrrole-2-carbaldehyde, 100g | CAS: 1003-29-8 | C5H5NO | 95.101 g/mol
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Catalog number ALFA12838.14
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Quantity:
25 g
Specifications
Chemical Name or MaterialPyrrole-2-carboxaldehyde
CAS1003-29-8
Health Hazard 1H315-H319-H335
Health Hazard 2GHS H Statement
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
H315-H319-H335
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Health Hazard 3P261-P264b-P271-P280-P302+P352-P304+P340-P305+P351+P338-P312-P332+P313-P362-P501c
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Pyrrole-2-carboxaldehyde is used as a pharmaceutical intermediate. It undergoes condensation reaction to produce pyrrole-2-carboxaldehyde salicylhydrazone (PCSH). It is used as a key starting material for the preparation of pyrrole -2-carboxylic acid by oxidation reaction. It is also used to prepare 4-Difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY dyes) through condensation with a pyrrole, which is an important probes for biotechnology and other applications.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
Pyrrole-2-carboxaldehyde is used as a pharmaceutical intermediate. It undergoes condensation reaction to produce pyrrole-2-carboxaldehyde salicylhydrazone (PCSH). It is used as a key starting material for the preparation of pyrrole -2-carboxylic acid by oxidation reaction. It is also used to prepare 4-Difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY dyes) through condensation with a pyrrole, which is an important probes for biotechnology and other applications.
Solubility
Soluble in chloroform, dimethyl sulfoxide and methanol. Insoluble in water.
Notes
Store in cool place. Air sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents, strong reducing agents and strong bases.
Pyrrole-2-carboxaldehyde is used as a pharmaceutical intermediate. It undergoes condensation reaction to produce pyrrole-2-carboxaldehyde salicylhydrazone (PCSH). It is used as a key starting material for the preparation of pyrrole -2-carboxylic acid by oxidation reaction. It is also used to prepare 4-Difluoro-4-bora-3a,4a-diaza-s-indacene (BODIPY dyes) through condensation with a pyrrole, which is an important probes for biotechnology and other applications.
Solubility
Soluble in chloroform, dimethyl sulfoxide and methanol. Insoluble in water.
Notes
Store in cool place. Air sensitive. Keep the container tightly closed in a dry and well-ventilated place. Incompatible with strong oxidizing agents, strong reducing agents and strong bases.
RUO – Research Use Only
General References:
- Rawat, P.; Singh, R. N. Eco-friendly synthesis, spectral and computational study of pyrrole-2-carboxaldehyde salicylhydrazone (PCSH) for its application. J. Mol. Struct. 2015, 1100, 105-115.
- Otaibi, A. A.; Gordon, C. P.; Gilbert, J.; Sakoff, J. A.; McCluskey, A. The influence of ionic liquids on the Knoevenagel condensation of 1H-pyrrole-2-carbaldehyde with phenyl acetonitriles - cytotoxic 3-substituted-(1H-pyrrol-2-yl)acrylonitriles. RSC Adv. 2015, 4 (38), 19806-19813.