N,N-Dimethyl-n-octylamine, 95%
N,N-Dimethyl-n-octylamine, 95%
N,N-Dimethyl-n-octylamine, 95%
N,N-Dimethyl-n-octylamine, 95%
Thermo Scientific Chemicals

N,N-Dimethyl-n-octylamine, 95%

CAS: 7378-99-6 | C10H23N | 157.30 g/mol
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Catalog NumberQuantity
ALFA12546.0910 g
Catalog number ALFA12546.09
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10 g
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Specifications
Chemical Name or MaterialN,N-Dimethyl-n-octylamine
CAS7378-99-6
Health Hazard 1H227-H301-H314
Health Hazard 2GHS H Statement
H301-H314-H318-H227
Toxic if swallowed.
Causes severe skin burns and eye damage.
Causes serious eye damage.
Combustible liquid.
Health Hazard 3P210-P260-P264b-P270-P280-P303+P361+P353-P304+P340-P305+P351+P338-P310-P330-P331-P363-P370+P378q-P501c
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N,N-Dimethyl-n-octylamine is used as ion-pairing agent in the quantitative estimation of thiazinamium methylsulphate in a pharmaceutical preparation by HPLC. It acts as a counterion in mobile phase for separation of tetracycline, tetracycline analogs and their potential impurities by reversed-phase ion-pair chromatography. Further, it is used in the study of chiral separations by complexation with proteins in capillary zone electrophoresis. In addition to this, it is used as a mobile phase in direct resolution and quantitation of (R)- and (S)-disopyramide

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
N,N-Dimethyl-n-octylamine is used as ion-pairing agent in the quantitative estimation of thiazinamium methylsulphate in a pharmaceutical preparation by HPLC. It acts as a counterion in mobile phase for separation of tetracycline, tetracycline analogs and their potential impurities by reversed-phase ion-pair chromatography. Further, it is used in the study of chiral separations by complexation with proteins in capillary zone electrophoresis. In addition to this, it is used as a mobile phase in direct resolution and quantitation of (R)- and (S)-disopyramide

Solubility
Slightly miscible with water.

Notes
Air sensitive. Incompatible with strong oxidizing agents, strong acids and copper.
RUO – Research Use Only

General References:

  1. Modifier for reverse-phase liquid chromatographic separation of amines.
  2. Matsukizono, H.; Endo, T. Synthesis of polyhydroxyurethanes from di(trimethylolpropane) and their application to quaternary ammonium chloride-functionalized films. RSC Adv. 2015, 5 (87), 71360-71369.
  3. Matsunaga, H.; Haginaka, J. Separation of enantiomers on chiral stationary phase based on chicken alpha 1-acid glycoprotein: Effect of silica particle diameters on column performance. J. Chromatogr. A 2014, 1363, 96-100.