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4-Nitrobenzoyl chloride, 98%
CAS: 122-04-3 | C7H4ClNO3 | 185.56 g/mol
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Catalog number ALFA12543.30
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Quantity:
250 g
Specifications
Chemical Name or Material4-Nitrobenzoyl chloride
CAS122-04-3
Health Hazard 1H314-H335
Health Hazard 2GHS H Statement
H314-H318
Causes severe skin burns and eye damage.
Causes serious eye damage.
H314-H318
Causes severe skin burns and eye damage.
Causes serious eye damage.
Health Hazard 3P260-P264b-P271-P280-P301+P330+P331-P303+P361+P353-P304+P340-P305+P351+P338-P310-P363-P501c
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4-Nitrobenzoyl chloride is used in the preparation of polysubstituted furanonaphthoquinoines. It is also involved in Michael addition, Henry reaction, O-alkylation and cycloaddition reactions. Further, it is employed as an intermediate in active pharmaceutical ingredient and dyes.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
4-Nitrobenzoyl chloride is used in the preparation of polysubstituted furanonaphthoquinoines. It is also involved in Michael addition, Henry reaction, O-alkylation and cycloaddition reactions. Further, it is employed as an intermediate in active pharmaceutical ingredient and dyes.
Solubility
Soluble in terahydrofuran, dichloromethane, chloroform and pyridine.
Notes
Moisture sensitive. Incompatible with water, alcohols, oxidizing agents and strong bases.
4-Nitrobenzoyl chloride is used in the preparation of polysubstituted furanonaphthoquinoines. It is also involved in Michael addition, Henry reaction, O-alkylation and cycloaddition reactions. Further, it is employed as an intermediate in active pharmaceutical ingredient and dyes.
Solubility
Soluble in terahydrofuran, dichloromethane, chloroform and pyridine.
Notes
Moisture sensitive. Incompatible with water, alcohols, oxidizing agents and strong bases.
RUO – Research Use Only
General References:
- Reagent for the preparation of crystalline esters.
- Chen, W.; Feng, Y.; Zhang, M.; Wu, J.; Zhang, J.; Gao, X.; He, J.; Zhang, J. Homogeneous benzoylation of cellulose in 1-allyl-3-methylimidazolium chloride: Hammett correlation, mechanism and regioselectivity. RSC Adv. 2015, 5 (72), 58536-58542.
- Skácel, J.; Budka, J.; Eigner, V.; Lhoták, P. Regioselective Friedel-Crafts acylation of calix[4]arenes. Tetrahedron 2015, 71 (13), 1959-1965.