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2-Fluoropyridine, 99%
CAS: 372-48-5 | C5H4FN | 97.092 g/mol
| Catalog Number | Quantity |
|---|---|
| ALFA11627.09 | 10 g |
Catalog number ALFA11627.09
Price (MYR)
324.00
EA
Quantity:
10 g
Price (MYR)
324.00
EA
Specifications
Chemical Name or Material2-Fluoropyridine
CAS372-48-5
Health Hazard 1H226-H302+H312+H332-H315-H319-H335
Health Hazard 2GHS H Statement
H226-H315-H319-H335
Flammable liquid and vapor.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
H226-H315-H319-H335
Flammable liquid and vapor.
Causes skin irritation.
Causes serious eye irritation.
May cause respiratory irritation.
Health Hazard 3P210-P233-P235-P240-P241-P242-P243-P261-P264b-P270-P271-P280-P301+P312-P303+P361+P353-P304+P340-P305+P351+P338-P312-P330-P332+P313-P363-P370+P378q-P501c
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2-Fluoropyridine is a useful precursor of 2,3-disubstituted pyridines which is made by the possibility of metallation at C-3, together with the ready nucleophilic displacement of the activated fluorine. It can also react with thiophene to get 2-thiophen-2-yl-pyridine. It is used in the synthesis of aminopyridines.
This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.
Applications
2-Fluoropyridine is a useful precursor of 2,3-disubstituted pyridines which is made by the possibility of metallation at C-3, together with the ready nucleophilic displacement of the activated fluorine. It can also react with thiophene to get 2-thiophen-2-yl-pyridine. It is used in the synthesis of aminopyridines.
Solubility
Soluble in water.
Notes
Store in a cool, dry, well-ventilated area away from incompatible substances such as oxidizing agents.
2-Fluoropyridine is a useful precursor of 2,3-disubstituted pyridines which is made by the possibility of metallation at C-3, together with the ready nucleophilic displacement of the activated fluorine. It can also react with thiophene to get 2-thiophen-2-yl-pyridine. It is used in the synthesis of aminopyridines.
Solubility
Soluble in water.
Notes
Store in a cool, dry, well-ventilated area away from incompatible substances such as oxidizing agents.
RUO – Research Use Only
General References:
- Lubov Pasumansky; Armando R. Hernández; Soya Gamsey; Christian T. Goralskib; Bakthan Singaram. Synthesis of aminopyridines from 2-fluoropyridine and lithium amides. Tetrahedron Letters.2004, 45 413-417.
- The possibility of metallation at C-3, together with the ready nucleophilic displacement of the activated fluorine makes 2-fluoropyridine a useful precursor of a wide range of 2,3-disubstituted pyridines. See, e.g.: J. Org. Chem., 53, 2740 (1988):