D-(+)-Mannose, 99%

CAS: 3458-28-4 | C₆H₁₂O₆

Catalog Number	Quantity
ALFA10842.14	25 g

Catalog number ALFA10842.14

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Specifications

Chemical Name or MaterialD-(+)-Mannose

CAS3458-28-4

Melting Point127°C to 133°C

Recommended StorageAmbient temperatures

Density1.54 g/mL

D-mannose acts as an alternative energy source utilized by brain. It is used in the study of assessing the synthesis of amphiphilic glycopolymers and investigating early detection of bronchiolitis obliterans.It may be useful in the treatment of urinary tract infections (UTIs) and carbohydrate-deficient glycoprotein syndrome type 1b. It is also useful in the formation of glycan structure and glycosylation.

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Scientific Chemicals.

Applications
D-mannose acts as an alternative energy source utilized by brain. It is used in the study of assessing the synthesis of amphiphilic glycopolymers and investigating early detection of bronchiolitis obliterans.It may be useful in the treatment of urinary tract infections (UTIs) and carbohydrate-deficient glycoprotein syndrome type 1b. It is also useful in the formation of glycan structure and glycosylation.

Solubility
Soluble in water.

Notes
Hygroscopic. Incompatible with strong oxidizing agents.

RUO – Research Use Only

General References:

Chiral building block. For use in a 15-step synthesis of the macrocycle (+)-aspicilin, in which 3 of the 4 asymmetric centers come from mannose, see: Helv. Chim. Acta, 72, 1753 (1989).
Nakagawa, Y.; Watanabe, Y.; Igarashi, Y.; Ito, Y.; Ojika, M. Pradimicin A, a d-mannose-binding antibiotic, binds pyranosides of l-fucose and l-galactose in a calcium-sensitive manner. Bioorg. Med. Chem. Lett. 2015, 25 (15), 2963-2966.
Zhai, Y.; Dasog, M.; Snitynsky, R. B.; Purkait, T. K.; Aghajamali, M.; Hahn, A. H.; Sturdy, C. B.; Lowary, T. L.; Veinot, J. G. C. Water-soluble photoluminescent D-mannose and L-alanine functionalized silicon nanocrystals and their application to cancer cell imaging. J. Mater. Chem. B 2014, 2 (47), 8427-8433.