ProPac™ SAX-10 HPLC Columns

Use Thermo Scientific™ ProPac™ SAX-10 LC Columns for exceptionally high resolution and efficiency when separating protein variants. Based on a nonporous 10μm core particle that provides pressure stability, ProPac columns can resolve isoforms that differ by a single charged residue. A thin, hydrophilic layer prevents unwanted secondary interactions. The grafted anion-exchange surface provides pH-based selectivity control and fast mass transfer for high-efficiency separation and moderate capacity.

Maximizing Resolution

• ProPac SAX-10 LC column is a strong anion-exchanger with a quaternary amine functional group.
• Column sizes range from 2mm I.D., for analytical work, up to 22mm I.D. for semiprep work.

Superior Performance for Protein Analysis

• Ideal for characterization and quality control assessment of closely-related protein variants
• Unequaled high-resolution separations
• High-efficiency peaks with excellent recovery
• Higher capacity than other columns based on nonporous particles
• Superior column-to-column and lot-to-lot reproducibility eliminates column variability as a concern in stability and QA/QC testing